ATI Pharm Made Easy – Immunology

When caring for a patient who is taking flutamide to treat prostate cancer, the health care professional should monitor the patient for which of the following adverse effects of the drug?Gynecomastia

(Flutamide, an androgen receptor blocker, treats early and metastatic prostate cancer. Can cause gynecomastia, decreased libido, and impotence)

A health care professional is caring for a patient who is about to begin maraviroc (Selzentry) therapy. The health care professional should tell the patient to report which of the following adverse effects of the drug? SATA-Parasthesias
(as well as dizziness and musculoskeletal pain)
-Cough
(as well as respiratory infection)
-Jaundice
(can cause liver damage. A rash can precede liver damage, manifested as jaundice or abdominal pain)
-Fever
(can cause a fever and sinner infection)
While assessing a patient who is receiving interferon alfa-2a (Roferon-A) to treat Kaposi’s sarcoma, the health care professional should check for which of the following possible indications of an adverse reaction?Fever
(This medication can cause a flu-like reaction, manifesting as a fever, myalgia, and fatigue)
When talking to a patient who is about to begin vincristine therapy to treat lymphoma, the health care professional should include which of the following instructions?Increase fiber intake
(Can cause severe constipation and upper colon fecal impaction)
A health care professional should question the use of maraviroc (Selzentry)for a patient who has which of the following ?Non-chemokine receptor 5 (CCR5)-tropic HIV-1
(acts by binding to CCR5 and preventing HIV-1 from entering the cell)
A health care professional should understand that enfuvirtide (Fuzeon) is an appropriate choice for patients who have which of the following?Advanced HIV disease
(treats HIV that is advanced or resistant to other types of treatment. Always give the drug along with other antiretroviral drugs)
Unless there are specific contraindications, which of the following immunizations should adults receive once each year?Influenza
A health care professional is caring for a patient who is about to begin intrathecal cytarabine (DepoCyt) therapy to treat meningeal leukemia. The health care professional should explain that the patient should also receive which of the following drugs to reduce the risk of neurotoxicity?Dexamethasone
(a glucocorticoid that helps decrease the inflammation of the arachnoid that is caused by cytarabine)
A health care professional is caring for a patient who is about to begin delavirdine (Rescriptor)therapy to treat HIV-1. The health care professional should tell the patient to report which of the following adverse reactions to the drug?Rash
(can develop into Stevens-Johnson syndrome)
A health care professional is caring for a patient who is about to start ritonavir (Norvir) and zidovudine (Retrovir) therapy to treat HIV-1. The health care professional should explain that the patient will receive ritonavir along with at least one reverse transcriptase inhibitor toprevent drug resistance
A health care professional is caring for a patient who is about to begin topotecan (Hycamtin) therapy to treat resistant, small-cell lung cancer. The health care professional should caution the patient about taking which of the following types of over-the-counter drugs while receiving therapy?Ibuprofen
(NSAIDs, anticoagulants, and antiplatelet drugs increase the patients risk for bleeding while receiving topotecan)
When caring for a patient who is receiving vincristine to treat lung cancer, the health care professional should monitor for which of the following findings that indicate an adverse effect?Weak hand grasps
(Vincristine can cause peripheral neuropathy. Monitor deep tendon-reflexes and the strength and movement of the hands and feet. Report paresthesias or reduced sensation in the hands or feet)
A health care professional is caring for a patient who is about to begin taking mercaptopurine (Purinethol) to treat leukemia. Which of the following instructions should the health care professional include when talking with the patient about the drug?-Use contraception if pregnancy is a risk
-Perform oral hygiene frequently
(can cause stomatitis)
-Perform hand hygiene frequently
(can cause neutropenia)
-Avoid activities that can cause injury
(can cause thrombocytopenia)
A health care professional is caring for a patient who is about to begin tamoxifen (Soltamox) to treat breast cancer. The health care professional should recognize the need for cautious use of the drug of the patient also has which of the following?Cataracts
(Tamoxifan, an estrogen receptor blocker, can cause retinopathy, cataracts, and decreased visual acuity)
When talking with a patient who is about to begin taking methotrexate (Trexall) therapy to treat non-Hodgkin lymphoma, the health care professional should include which of the following instructions?Use a soft bristled toothbrush
(Can cause severe bone marrow suppression with decreased thrombocyte counts and also oral and GI ulceration. use soft bristled toothbrush to prevent gum bleeding and mouth trauma)
A health care professional is assessing a patient following a trastuzumab (Herceptin) infusion to treat metastatic breast cancer. Which of the following findings indicates an adverse reaction to the drug? SATA-Wheezing
(can cause a severe allergic reaction manifesting as hives, bronchospasm, hypotension, dyspnea, hypoxia, and wheezing )
-Dysrhythmias
(can cause cardiotoxicity)
-Hypotension
(can cause severe allergic reaction)
-Fever
(can cause flu-like reactions)
A health care professional is caring for a patient who is about to begin receiving cisplatin to treat testicular cancer. The health care professional should tell the patient to report which of the following adverse effects? SATA-Parasthesias
(can cause peripheral neuropathy – report numbness, tingling, or decreased sensation in the hands or feet)
-Sore throat
(can cause bone marrow suppression – report fever, sore throat, bruising, or fatigue)
-Flank pain
(can cause kidney toxicity)
-Tinnitus
(can cause toxicity – report hearing loss, vertigo, or tinnitus)
A health care professional should question the use of anastrozole (Arimidex) for a patient who ispremenopausal
A health care professional is caring for a patient who is receiving IV carmustine (BiCNU) to treat multiple myeloma. The health care professional should recognize that the patient is at the greatest risk for infection for which of the following lengths of time after the infusion?4 to 6 weeks
(can cause delayed bone marrow suppression)
A health care professional should understand that raltegravir (Isenstress) treats patients who have which of the following?Resistant HIV
A health care professional is about to administer infuvirtide (Fuzeon)to a patient. The health care professional should perform which of the following actions? SATA-Administer the drug subcutaneously (twice a day)
-Roll the vial gently to reconstitute the solution (also warm to room temperature prior to administration)
-Inject the solution at room temperature (can be stored in a fridge up to 24 hours but just be administered at room temp)
When considering drug therapy options for a patient who has metastatic breast cancer that is positive for epidermal growth factor receptor 2 (HER2), the health care professional should choose which of the following drugs?Trastuzumab
(treats metastatic breast cancer with tumors that over express)
A health care professional should question the use of cyclophosphamide for a patient who has which of the following?Dehydration
(contraindicated in patients with a fluid-volume deficit because it increases the risk for renal toxicity)
A health care professional is about to administer IV paclitaxel (Taxol) to a patient who has ovarian cancer. Which of the following actions should the health care professional take? SATA-Give the patient an antihistamine (to prevent a hypersensitivity reaction)
-Administer the drug thru non-PVC tubing (drug is incompatible with this type of tubing)
-Use an in-line filter
A health care professional is caring for a patient who is about to begin taking imatinib (Gleevac)to treat chronic myeloid leukemia. Which of the following instructions should the health care professional include when talking to the patient about taking the drug? SATA-Clean fruits and veggies thoroughly
(to prevent transmission of bacteria as this medication can cause bone marrow suppression)
-Weight yourself daily
(can cause fluid retention and weight gain)
-Perform hand hygiene frequently
(can cause bone marrow suppression)
-Avoid herbal supplements
(St. John’s wort can decrease imatinib levels)